Call: (979) 848-0800
DELIVERING, EXPANDING, ADVANCING The science of radiopharmaceuticals

About Us

IsoTherapeutics Group, LLC (IsoTherapeutics) is a radiopharmaceutical company that was founded in 2005 by two entrepreneur scientists with a passion for advancing the technology of radiopharmaceuticals. The company scientists, while employed at the Dow Chemical Company, developed QUADRAMET® a radiopharmaceutical for treatment of bone pain due to metastatic cancer, treatments for arthritis, osteoporosis, and osteomyelitis, just to name a few. IsoTherapeutics scientists have received over 100 patents for developing chemistry and radiopharmaceutical formulations.

IsoTherapeutics provides contract R&D and manufacturing services for the purpose of aiding our customers and collaborators in the development of pharmaceuticals. Our company scientists have extensive experience in chelation and radiochemistry, which can be applied to a variety of technologies. Our conjugation and radiolabeling capabilities allow us to radiolabel proteins or antibody conjugates, which are ideal for pre-clinical proof of concept research for radio-immunotherapy and diagnostic applications. The company has a radioactive materials license to handle numerous radioisotopes of interest to the radiopharmaceutical community. We have an animal testing facility which gives us the ability to perform bio-distribution and pharmacokinetic studies on normal or xenograft models using radiolabeled compounds.

With the increasing significance of biologics for diagnostic and therapeutic purposes in pharmaceutical applications, the ability to verify biomolecular localization in vitro and in vivo has become ever more important. We have been closely involved in early stage analysis and proof of concept in this type of application for numerous customers. Additionally, we collaborate with a number of imaging companies and their customers to provide conjugation/radiolabeling of biologics for pre-clinical technology assessments for both diagnostic and therapeutic applications. IsoTherapeutics opened its registered cGMP manufacturing facility equipped with clean rooms to facilitate many R&D and manufacturing opportunities. Finally, we have a wide array of analytical capabilities including GC, ICP, and HPLC with Rad, UV and RI capabilities and also a wide variety of radio-analytical counting equipment.

Our business model is to collaborate with companies, venture capitalist groups, universities, and medical centers that complement our offerings and technologies for developing novel diagnostic and therapeutic agents for severe diseases. Current collaborators are MD Anderson Cancer Center, Sidney Kimmel Comprehensive Cancer Center Johns Hopkins University, University of Missouri – Columbia, MI Bioresearch, Perkin Elmer and several other virtual or near-virtual biopharma companies.

While many of our collaborators are located widely across North America, for Texas-based companies we are conveniently located in Angleton, Texas, about 40 miles south of the Texas Medical Center. Our location makes us an ideal choice for early stage pre-clinical collaborators located in the southeast portion of Texas. We would be happy to discuss your research and technology efforts and invite you to visit our facility to learn more about us and our capabilities.


A small company with high caliber people. This company helped me address critical questions posed by the FDA.

Ebrahim S. Delpassand, M.D.
Chairman & Medical Director Excel Diagnostics

IsoTherapeutics has proven to be a partner able to adapt quickly to FUJIFILM's changing needs. Within two weeks, they had documentation in place for the preparation of two new blood testing kits, and prepared GMP batches of each for our clinical sites.

Takeaki Suzuki, Ph.D.
Associate Director, Drug Development, Head of Operations, FUJIFILM Pharmaceuticals USA, Inc.

The combination of R&D, cGMP and small animal testing facilities makes IsoTherapeutics the ideal partner for our radiopharmaceutical programs - from initial development to commercialization. The skills that IsoTherapeutics have brought to our product development programs over the past decade have proven to be a major contribution to our success.

Nigel R. Stevenson, Ph.D.
COO, Serene, LLC

Contact Us

IsoTherapeutics Group, LLC
1004 S. Velasco St.
Angleton, TX 77515

Phone (979) 848-0800
Fax (979) 848-0807