Call: (979) 848-0800
info@isotherapeutics.com
DELIVERING, EXPANDING, ADVANCING The science of radiopharmaceuticals

Facilities

   

IsoTherapeutics Group is located about 45 miles south of Houston at 1004 South Velasco Street in Angleton, Texas. The facility consists of three buildings equipped with offices, R&D laboratories, cGMP production area, documentation room, shipping and receiving, controlled storage areas and an animal research laboratory.

The laboratories are fully equipped with radiochemistry and analytical equipment for developing radiopharmaceutical products targeted at specific diseases. Our radio-analytical equipment includes a variety of instrumentation including an automated NaI gamma counter along with several stand-alone NaI detectors, two germanium detectors for gamma spectroscopy, a liquid scintillation counter, an alpha spectroscopy system, dose calibrators, and many survey meters. A Siemens gamma camera allows for the capture and analysis of in vivo images.

  

Additional equipment includes a PerkinElmer Optima 5300 inductively-coupled plasma optical emission spectrophotometer, four chemical fume hoods, three laminar flow hoods, an HP 6890 Series GC with HP 7694 headspace sampler, an HP series 1100 HPLC with both UV and radiometric detection, an Agilent series 1200 Infinity HPLC with diode array UV and radiometric detection, an Agilent series 1200 Infinity HPLC with mass spec, variable wavelength UV and radiometric detection and a PerkinElmer Cyclone Plus Phosphor Imager, which provides autoradiography capabilities.

We have biological equipment for growing cell lines such as CO2 incubator, -80oC freezer, a certified Biological Safety Cabinet. Additional equipment includes lyophilizer, rotary evaporators, environmental chambers for product studies, steam autoclave, and various microscopes. A 96-well plate washer & reader allow us to efficiently set up ELISA assays and polyacrylamide gel electrophoresis allows for protein characterization.

  

   

The 3600 sq ft cGMP facility encompasses four controlled environment rooms and a large general lab area to assist customers with radiopharmaceutical manufacturing under the FDA guideline 21 CFR 11. The facility is registered as a manufacturer with the FDA. The facility is equipped with the state-of-art equipment, such as class 5 lead-shielded isolators, laminar flow hoods, fume hoods, HPLC, LC-MS, autoclave, depyrogenation oven, and lyphollizer for making freeze-dried kits.

IsoTherapeutics holds a broad radioactive materials license from the State of Texas to handle a wide variety of radioisotopes. We have hands-on experience with most of the relevant medical radioisotopes.

The annex-building that houses our laboratory animals is equipped with a HEPA-filtered cabinet for housing athymic mice along with a PerkinElmer Wizard 3″ 1480 Automatic Gamma Counter to aid in bio-distribution studies. We own a variety of rodent cage types including metabolic cages for mice and rats. IsoTherapeutics is registered with the USDA as a Class R Research Facility under the Animal Welfare Act.

Testimonials

A small company with high caliber people. This company helped me address critical questions posed by the FDA.

Ebrahim S. Delpassand, M.D.
Chairman & Medical Director Excel Diagnostics

IsoTherapeutics has proven to be a partner able to adapt quickly to FUJIFILM's changing needs. Within two weeks, they had documentation in place for the preparation of two new blood testing kits, and prepared GMP batches of each for our clinical sites.

Takeaki Suzuki, Ph.D.
Associate Director, Drug Development, Head of Operations, FUJIFILM Pharmaceuticals USA, Inc.

The combination of R&D, cGMP and small animal testing facilities makes IsoTherapeutics the ideal partner for our radiopharmaceutical programs - from initial development to commercialization. The skills that IsoTherapeutics have brought to our product development programs over the past decade have proven to be a major contribution to our success.

Nigel R. Stevenson, Ph.D.
COO, Serene, LLC

Contact Us

IsoTherapeutics Group, LLC
1004 S. Velasco St.
Angleton, TX 77515

Phone (979) 848-0800
Fax (979) 848-0807
Email info@isotherapeutics.com